Andres Iniesta who scored the World Cup winning goal against Netherlands will make an emotional return to the venue that catapulted him to fame when he was named in the travelling team on Thursday.
Iniesta is among a galaxy of Spanish big names that will take on Bafana Bafana on 19 November 2013 at FNB Stadium, the venue that hosted the 2010 FIFA World Cup final.
It is a squad teeming with world class luminaries that ply their trade in top European leagues.
Diego Costa is in line to make his Spain debut against Bafana Bafana after being named in their squad.
The red-hot Atletico Madrid striker has turned down the opportunity to play for Brazil, and Bafana could bear the brunt of that if he gets the nod at Soccer City.
Barcelona superstar Xavi Hernandez will be missing, but there is still plenty of talent about, including the likes of Cesc Fabregas, Javi Martinez and Real Madrid’s Iker Casillas, Sergio Ramos and Xabi Alonso.
English Premiership stars Santo Carzola, Jesus Navas, Alvaro Negredo and Juan Mata will also make the trip.
Goalkeepers: Iker Casillas (Real Madrid), Victor Valdes (Barcelona), Pepe Reina (Napoli)
Defenders: Alvaro Arbeloa (Real Madrid), Raul Albiol (Napoli), Sergio Ramos (Real Madrid), Alberto Moreno (Sevilla), Juanfran (Levante), Javi Martinez (Bayern Munich), Inigo Martinez (Real Sociedad), Nacho Monreal (Arsenal)
Midfielders: Sergio Busquets (Barcelona), Xabi Alonso (Real Madrid), Koke (Atletico Madrid), Andres Iniesta (Barcelona), Santi Cazorla (Arsenal), Cesc Fabregas (Barcelona), Jesus Navas (Manchester City)
Forwards: Alvaro Negredo (Manchester City), Diego Costa (Atletico Madrid), Pedro (Barcelona), David Villa (Atletico Madrid), Juan Mata (Chelsea)